Varaico: Literature-Extracted Genetic Variants

ADGRB2

137 papers

RefSeq Summary

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature pep...

Pfam Domains

AGRB_Naa 38–230UCSCAdhesion GPCR B N-terminal region

TSP_1aa 313–361UCSCThrombospondin type 1 domain

TSP_1aa 368–416UCSCThrombospondin type 1 domain

TSP_1aa 423–471UCSCThrombospondin type 1 domain

TSP_1aa 479–527UCSCThrombospondin type 1 domain

GAINaa 596–706UCSCAGRL2-4 GAIN subdomain A

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor B2

HGNC Previous Symbol

BAI2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001364857.2

p.S736I

c.2207G>T

Surrounding Variants

1 paper

NM_001364857.2

p.M742L

c.2224A>T

1 paper

NM_001364857.2

p.M742L

c.2224A>C

1 paper

NM_001364857.2

p.I726fs

c.2176_2177fs

1 paper

NM_001364857.2

p.V765L

c.2293G>T

1 paper

NM_001364857.2

p.V765L

c.2293G>C

1 paper

NM_001364857.2

p.P774L

c.2321C>T

1 paper

NM_001364857.2

p.P783L

c.2348C>T

1 paper

NM_001364857.2

p.T791M

c.2372C>T

1 paper

NM_001364857.2

p.D807Y

c.2419G>T

1 paper

NM_001364857.2

p.V819L

c.2455G>T

1 paper

NM_001364857.2

p.V819L

c.2455G>C

1 paper

NM_001364857.2

p.R822H

c.2465G>A