Varaico: Literature-Extracted Genetic Variants

ADGRB2

137 papers

RefSeq Summary

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature pep...

Pfam Domains

AGRB_Naa 38–230UCSCAdhesion GPCR B N-terminal region

TSP_1aa 313–361UCSCThrombospondin type 1 domain

TSP_1aa 368–416UCSCThrombospondin type 1 domain

TSP_1aa 423–471UCSCThrombospondin type 1 domain

TSP_1aa 479–527UCSCThrombospondin type 1 domain

GAINaa 596–706UCSCAGRL2-4 GAIN subdomain A

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor B2

HGNC Previous Symbol

BAI2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001364857.2

p.F665V

c.1993T>G

Surrounding Variants

1 paper

NM_001364857.2

p.D683N

c.2047G>A

1 paper

NM_001364857.2

p.H693Q

c.2079C>G

1 paper

NM_001364857.2

p.H693Q

c.2079C>A

1 paper

NM_001364857.2

p.L694L

c.2080C>T

2 papers

NM_001364857.2

p.R696C

c.2086C>T

1 paper

NM_001364857.2

p.R696H

c.2087G>A

1 paper

NM_001364857.2

p.R628Q

c.1883G>A

1 paper

NM_001364857.2

p.A611S

c.1831G>T

1 paper

NM_001364857.2

p.R608L

c.1823G>T

1 paper

NM_001364857.2

p.E601*

c.1801G>T

1 paper

NM_001364857.2

p.I726fs

c.2176_2177fs

1 paper

NM_001364857.2

p.S736I

c.2207G>T