Varaico: Literature-Extracted Genetic Variants

ADGRB2

137 papers

RefSeq Summary

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature pep...

Pfam Domains

AGRB_Naa 38–230UCSCAdhesion GPCR B N-terminal region

TSP_1aa 313–361UCSCThrombospondin type 1 domain

TSP_1aa 368–416UCSCThrombospondin type 1 domain

TSP_1aa 423–471UCSCThrombospondin type 1 domain

TSP_1aa 479–527UCSCThrombospondin type 1 domain

GAINaa 596–706UCSCAGRL2-4 GAIN subdomain A

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor B2

HGNC Previous Symbol

BAI2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001364857.2

p.P147P

c.441C>A

Surrounding Variants

1 paper

NM_001364857.2

p.F148I

c.442T>A

1 paper

NM_001364857.2

p.A137V

c.410C>T

1 paper

NM_001364857.2

p.S167S

c.501C>T

1 paper

NM_001364857.2

p.R127W

c.379C>T

1 paper

NM_001364857.2

p.R171H

c.512G>A

4 papers

NM_001364857.2

p.P175P

c.525C>T

1 paper

NM_001364857.2

p.R181H

c.542G>A

1 paper

NM_001364857.2

p.R203C

c.607C>T

1 paper

NM_001364857.2

p.R203L

c.608G>T

1 paper

NM_001364857.2

p.R85H

c.254G>A

1 paper

NM_001364857.2

p.R210C

c.628C>T

1 paper

NM_001364857.2

p.R82C

c.244C>T