adhesion G protein-coupled receptor E3

EMR3

egf-like module containing, mucin-like, hormone receptor-like 3

Adhesion G protein-coupled receptor E3

EGF-like module receptor 3

EGF-like module-containing mucin-like hormone receptor-like 3

7 transmembrane receptor (Secretin family)

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014].

Varaico: Literature-Extracted Genetic Variants

ADGRE3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol