Varaico: Literature-Extracted Genetic Variants

ADGRL2

97 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleave...

Pfam Domains

SUEL_Lectinaa 49–129UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 131–395UCSCOlfactomedin-like domain

OLFaa 135–399UCSCOlfactomedin-like domain

HRMaa 466–524UCSCHormone receptor domain

GAINaa 530–656UCSCAGRL2-4 GAIN subdomain A

GPSaa 790–834UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L2

HGNC Previous Symbols

LPHH1; LPHN2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 103 variants

2 papers

NM_001366006.2

p.C606C

c.1818C>T

2 papers

NM_001366006.2

p.N1252D

c.3754A>G

1 paper

NM_001366006.2

p.R9Q

c.26G>A

1 paper

NM_001366006.2

p.P21T

c.61C>A

1 paper

NM_001366006.2

p.F26S

c.77T>C

1 paper

NM_001366006.2

p.A29S

c.85G>T

1 paper

NM_001366006.2

p.G34E

c.101G>A

1 paper

NM_001366006.2

p.E43*

c.127G>T

1 paper

NM_001366006.2

p.P52Q

c.155C>A

1 paper

NM_001366006.2

p.P52P

c.156G>A

1 paper

NM_001366006.2

p.G53V

c.158G>T

1 paper

NM_001366006.2

p.V56D

c.167T>A