Varaico: Literature-Extracted Genetic Variants

ADGRL2

97 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleave...

Pfam Domains

SUEL_Lectinaa 49–129UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 131–395UCSCOlfactomedin-like domain

OLFaa 135–399UCSCOlfactomedin-like domain

HRMaa 466–524UCSCHormone receptor domain

GAINaa 530–656UCSCAGRL2-4 GAIN subdomain A

GPSaa 790–834UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L2

HGNC Previous Symbols

LPHH1; LPHN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001366006.2

p.R9Q

c.26G>A

Surrounding Variants

1 paper

NM_001366006.2

p.P21T

c.61C>A