Varaico: Literature-Extracted Genetic Variants

ADGRL2

97 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleave...

Pfam Domains

SUEL_Lectinaa 49–129UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 131–395UCSCOlfactomedin-like domain

OLFaa 135–399UCSCOlfactomedin-like domain

HRMaa 466–524UCSCHormone receptor domain

GAINaa 530–656UCSCAGRL2-4 GAIN subdomain A

GPSaa 790–834UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L2

HGNC Previous Symbols

LPHH1; LPHN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001366006.2

p.E1460A

c.4379A>C

Surrounding Variants

1 paper

NM_001366006.2

p.L1423F

c.4267C>T

1 paper

NM_001366006.2

p.D1390Y

c.4168G>T

1 paper

NM_001366006.2

p.A1369S

c.4105G>T

1 paper

NM_001366006.2

p.S1355F

c.4064C>T

1 paper

NM_001366006.2

p.R1341G

c.4021C>G

1 paper

NM_012302.5

p.L1262H

c.3785T>A

1 paper

NM_001366006.2

p.S1316P

c.3946T>C

1 paper

NM_001366006.2

p.A1315T

c.3943G>A

1 paper

NM_001366006.2

p.G1302R

c.3904G>A

2 papers

NM_001366006.2

p.N1252D

c.3754A>G

1 paper

NM_001366006.2

p.N1239D

c.3715A>G

1 paper

NM_001366006.2

p.A1213Splc

c.3637+260G>A