Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001387552.1

p.E24K

c.70G>A

Surrounding Variants

1 paper

NM_001387552.1

p.R25*

c.73C>T

1 paper

NM_001387552.1

p.H26delFs

c.76delC

1 paper

NM_001387552.1

p.H26fs

c.76_77fs

1 paper

NM_001387552.1

p.E56Q

c.166G>C

1 paper

NM_001387552.1

p.R62C

c.184C>T

1 paper

NM_001387552.1

p.Q64*

c.190C>T

1 paper

NM_001387552.1

p.G68R

c.202G>A

1 paper

NM_001387552.1

p.A84T

c.250G>A