Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001387552.1

p.D220Y

c.658G>T

Surrounding Variants

1 paper

NM_001387552.1

p.H221Y

c.661C>T

1 paper

NM_001387552.1

p.G224E

c.671G>A

1 paper

NM_001387552.1

p.D229H

c.685G>C

1 paper

NM_001387552.1

p.V210A

c.629T>C

1 paper

NM_001387552.1

p.L202V

c.604C>G

1 paper

NM_001387552.1

p.P241L

c.722C>T

1 paper

NM_001387552.1

p.V200Splc

c.599-6C>T

1 paper

NM_001387552.1

p.W242*

c.726G>A

1 paper

NM_001387552.1

p.P244P

c.732C>A

1 paper

NM_001387552.1

p.R246T

c.737G>C

1 paper

NM_001387552.1

p.T267N

c.800C>A

1 paper

NM_001387552.1

p.K269T

c.806A>C