Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001387552.1

p.D408G

c.1223A>G

Surrounding Variants

1 paper

NM_001387552.1

p.N400I

c.1199A>T

1 paper

NM_001387552.1

p.V394V

c.1182A>C

1 paper

NM_001387552.1

p.N380Y

c.1138A>T

1 paper

NM_001387552.1

p.V452I

c.1354G>A

1 paper

NM_001387552.1

p.S456F

c.1367C>T

1 paper

NM_001387552.1

p.I355M

c.1065T>G

1 paper

NM_001387552.1

p.L462P

c.1385T>C

1 paper

NM_001387552.1

p.V354I

c.1060G>A

1 paper

NM_001387552.1

p.S464C

c.1390A>T

1 paper

NM_001387552.1

p.K352T

c.1055A>C

1 paper

NM_001387552.1

p.R465K

c.1394G>A

2 papers

NM_001387552.1

p.R465S

c.1395A>C