Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001387552.1

p.F783L

c.2347T>C

Surrounding Variants

1 paper

NM_001387552.1

p.F783L

c.2349T>A

1 paper

NM_001387552.1

p.F783L

c.2349T>G

1 paper

NM_001387552.1

p.D780N

c.2338G>A

1 paper

NM_001387552.1

p.D780Y

c.2338G>T

1 paper

NM_001387552.1

p.L772L

c.2316G>A

1 paper

NM_001387552.1

p.L800F

c.2400A>C

1 paper

NM_001387552.1

p.L800F

c.2400A>T

2 papers

NM_001387552.1

p.R805Q

c.2414G>A

1 paper

NM_001387552.1

p.R732C

c.2194C>T

2 papers

NM_001387552.1

p.T727A

c.2179A>G

1 paper

NM_001387552.1

p.L725V

c.2173C>G

1 paper

NM_001387552.1

p.R723K

c.2168G>A