Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001387552.1

p.V872A

c.2615T>C

Surrounding Variants

1 paper

NM_001387552.1

p.T871I

c.2612C>T

1 paper

NM_001387552.1

p.Y863_L864insC

c.2587_2591ins3

1 paper

NM_001387552.1

p.I854I

c.2562A>C

1 paper

NM_001387552.1

p.T851M

c.2552C>T

1 paper

NM_001387552.1

p.I850I

c.2550T>C

1 paper

NM_001387552.1

p.T839A

c.2515A>G

1 paper

NM_001387552.1

p.E826V

c.2477A>T

1 paper

NM_001387552.1

p.T825R

c.2474C>G

1 paper

NM_001387552.1

p.V814I

c.2440G>A

1 paper

NM_001387552.1

p.A812V

c.2435C>T

1 paper

NM_001387552.1

p.A812delFs

c.2434delG

1 paper

NM_001387552.1

p.E880G

c.2639A>G