Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_001387552.1

p.L928V

c.2782C>G

Surrounding Variants

1 paper

NM_001387552.1

p.A926G

c.2777C>G

1 paper

NM_001387552.1

p.A926P

c.2776G>C

1 paper

NM_001387552.1

p.N920H

c.2758A>C

1 paper

NM_001387552.1

p.G904R

c.2710G>C

1 paper

NM_001387552.1

p.Q903*

c.2707C>T

1 paper

NM_001387552.1

p.T897I

c.2690C>T

1 paper

NM_001387552.1

p.R894L

c.2681G>T

1 paper

NM_001387552.1

p.S890R

c.2670C>A

1 paper

NM_001387552.1

p.S890R

c.2670C>G

1 paper

NM_001387552.1

p.S890R

c.2668A>C

1 paper

NM_001387552.1

p.E880G

c.2639A>G

1 paper

NM_001387552.1

p.V872A

c.2615T>C