Varaico: Literature-Extracted Genetic Variants

ADGRL3

127 papers

RefSeq Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human sp...

Pfam Domains

SUEL_Lectinaa 111–191UCSCD-galactoside/L-rhamnose binding SUEL lectin domain

OLFaa 198–462UCSCOlfactomedin-like domain

HRMaa 563–621UCSCHormone receptor domain

GAINaa 623–749UCSCAGRL2-4 GAIN subdomain A

7tm_2aa 861–1097UCSC7 transmembrane receptor (Secretin family)

GPSaa 884–928UCSCGPCR proteolysis site, GPS, motif

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor L3

HGNC Previous Symbol

LPHN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001387552.1

p.E1039V

c.3116A>T

Surrounding Variants

2 papers

NM_001387552.1

p.V1038V

c.3114G>C

1 paper

NM_001387552.1

p.F1019F

c.3057C>T

1 paper

NM_001387552.1

p.A1068V

c.3203C>T

1 paper

NM_001387552.1

p.V1010A

c.3029T>C

1 paper

NM_001387552.1

p.V1010I

c.3028G>A

1 paper

NM_001387552.1

p.V1079I

c.3235G>A

1 paper

NM_001387552.1

p.I997S

c.2990T>G

2 papers

NM_001387552.1

p.L996V

c.2986C>G

1 paper

NM_001387552.1

p.L994P

c.2981T>C

1 paper

NM_001387552.1

p.L954L

c.2862G>A