Varaico: Literature-Extracted Genetic Variants

Gene:ADRA1A
Variant:p.A422D

ADRA1A

134 papers

RefSeq Summary

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3...

Pfam Domains

7tm_1aa 43–326UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

adrenoceptor alpha 1A

HGNC Previous Symbol

ADRA1C

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000680.4
p.A422D
c.1265C>A
Surrounding Variants
1 paper
NM_000680.4
p.T420A
c.1258A>G
1 paper
NM_000680.4
p.K427R
c.1280A>G
1 paper
NM_000680.4
p.Q431*
c.1291C>T
3 papers
NM_000680.4
p.Q431E
c.1291C>G
1 paper
NM_000680.4
p.C435F
c.1304G>T
1 paper
NM_000680.4
p.R405H
c.1214G>A
1 paper
NM_000680.4
p.T440N
c.1319C>A
1 paper
NM_000680.4
p.P441L
c.1322C>T
1 paper
NM_000680.4
p.F400L
c.1198T>C
1 paper
NM_000680.4
p.K445K
c.1335G>A
1 paper
NM_000680.4
p.P450P
c.1350A>C
1 paper
NM_000680.4
p.T391M
c.1172C>T
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