Varaico: Literature-Extracted Genetic Variants

Gene:ADRA1A
Variant:p.F400L

ADRA1A

134 papers

RefSeq Summary

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3...

Pfam Domains

7tm_1aa 43–326UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

adrenoceptor alpha 1A

HGNC Previous Symbol

ADRA1C

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000680.4
p.F400L
c.1198T>C
Surrounding Variants
1 paper
NM_000680.4
p.R405H
c.1214G>A
1 paper
NM_000680.4
p.T391M
c.1172C>T
1 paper
NM_000680.4
p.R387K
c.1160G>A
2 papers
NM_000680.4
p.S381L
c.1142C>T
1 paper
NM_000680.4
p.T420A
c.1258A>G
1 paper
NM_000680.4
p.A422D
c.1265C>A
1 paper
NM_000680.4
p.R376H
c.1127G>A
1 paper
NM_000680.4
p.K427R
c.1280A>G
1 paper
NM_000680.4
p.Q431*
c.1291C>T
3 papers
NM_000680.4
p.Q431E
c.1291C>G
1 paper
NM_000680.4
p.V367M
c.1099G>A
1 paper
NM_000680.4
p.C435F
c.1304G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."