Varaico: Literature-Extracted Genetic Variants

Gene:ADRA2B
Variant:p.T265I

ADRA2B

120 papers

RefSeq Summary

This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves a...

Pfam Domains

7tm_1aa 29–426UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

adrenoceptor alpha 2B

HGNC Previous Symbols

ADRA2L1; ADRA2RL1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000682.7
p.T265I
c.794C>T
Surrounding Variants
1 paper
NM_000682.7
p.P262P
c.786T>C
1 paper
NM_000682.7
p.R268W
c.802C>T
1 paper
NM_000682.7
p.A269V
c.806C>T
1 paper
NM_000682.7
p.A269A
c.807C>T
1 paper
NM_000682.7
p.K256N
c.768G>T
1 paper
NM_000682.7
p.K256N
c.768G>C
1 paper
NM_000682.7
p.Q284*
c.850C>T
1 paper
NM_000682.7
p.K285M
c.854A>T
1 paper
NM_000682.7
p.C289Y
c.866G>A
1 paper
NM_000682.7
p.P293A
c.877C>G
1 paper
NM_000682.7
p.E294A
c.881A>C
1 paper
NM_000682.7
p.E294delins
c.881_882delinsCT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."