Varaico: Literature-Extracted Genetic Variants

Gene:AFP
Variant:p.D154V

AFP

574 papers

RefSeq Summary

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma an...

Pfam Domains

Serum_albuminaa 30–202UCSCSerum albumin family
Serum_albuminaa 222–394UCSCSerum albumin family
Serum_albuminaa 414–592UCSCSerum albumin family

Gene Aliases

HGNC Name

alpha fetoprotein

HGNC Previous Symbol

HPAFP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001134.3
p.D154V
c.461A>T
Surrounding Variants
1 paper
NM_001134.3
p.R155K
c.464G>A
1 paper
NM_001134.3
p.E153K
c.457G>A
1 paper
NM_001134.3
p.Y151delFs
c.451_452delTA
1 paper
NM_001134.3
p.S147delFs
c.439delA
1 paper
NM_001134.3
p.K161Splc
c.482+5G>A
1 paper
NM_001134.3
p.P144_V145insFs
c.432_433insA
1 paper
NM_001134.3
p.V141G
c.422T>G
1 paper
NM_001134.3
p.Q140K
c.418C>A
1 paper
NM_001134.3
p.L138H
c.413T>A
1 paper
NM_001134.3
p.I136I
c.408C>A
1 paper
NM_001134.3
p.A134V
c.401C>T
1 paper
NM_001134.3
p.P131S
c.391C>T
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