Varaico: Literature-Extracted Genetic Variants

AGO3

77 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role ...

Pfam Domains

ArgoNaa 28–167UCSCN-terminal domain of argonaute

ArgoL1aa 177–227UCSCArgonaute linker 1 domain

PAZaa 234–366UCSCPAZ domain

ArgoL2aa 375–421UCSCArgonaute linker 2 domain

ArgoMidaa 430–512UCSCMid domain of argonaute

Piwiaa 518–819UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC catalytic component 3

HGNC Previous Symbol

EIF2C3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 214 variants

3 papers

NM_024852.4

p.R689*

c.2065C>T

2 papers

NM_024852.4

p.M235I

c.705G>A

2 papers

NM_024852.4

p.M235I

c.705G>C

2 papers

NM_024852.4

p.M235I

c.705G>T

2 papers

NM_024852.4

p.P324L

c.971C>T

2 papers

NM_024852.4

p.P327L

c.980C>T

2 papers

NM_024852.4

p.G332R

c.994G>A

2 papers

NM_024852.4

p.G332R

c.994G>C

2 papers

NM_024852.4

p.R426W

c.1276C>T

2 papers

NM_024852.4

p.V435E

c.1304T>A

2 papers

NM_024852.4

p.E465G

c.1394A>G

1 paper

NM_024852.4

p.G4G

c.12C>T