Varaico: Literature-Extracted Genetic Variants

Gene:AGO3
Variant:p.S5Y

AGO3

77 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role ...

Pfam Domains

ArgoNaa 28–167UCSCN-terminal domain of argonaute
ArgoL1aa 177–227UCSCArgonaute linker 1 domain
PAZaa 234–366UCSCPAZ domain
ArgoL2aa 375–421UCSCArgonaute linker 2 domain
ArgoMidaa 430–512UCSCMid domain of argonaute
Piwiaa 518–819UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC catalytic component 3

HGNC Previous Symbol

EIF2C3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_024852.4
p.S5Y
c.14C>A
Surrounding Variants
1 paper
NM_024852.4
p.G4G
c.12C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."