Varaico: Literature-Extracted Genetic Variants

AGO3

77 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role ...

Pfam Domains

ArgoNaa 28–167UCSCN-terminal domain of argonaute

ArgoL1aa 177–227UCSCArgonaute linker 1 domain

PAZaa 234–366UCSCPAZ domain

ArgoL2aa 375–421UCSCArgonaute linker 2 domain

ArgoMidaa 430–512UCSCMid domain of argonaute

Piwiaa 518–819UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC catalytic component 3

HGNC Previous Symbol

EIF2C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024852.4

p.M235I

c.705G>T

Surrounding Variants

2 papers

NM_024852.4

p.M235I

c.705G>A

2 papers

NM_024852.4

p.M235I

c.705G>C

1 paper

NM_024852.4

p.M235K

c.704T>A

1 paper

NM_024852.4

p.Q233H

c.699G>T

1 paper

NM_024852.4

p.V238D

c.713T>A

1 paper

NM_024852.4

p.K227Q

c.679A>C

1 paper

NM_024852.4

p.D245E

c.735T>A

1 paper

NM_024852.4

p.P248S

c.742C>T

1 paper

NM_024852.4

p.R249G

c.745A>G

1 paper

NM_024852.4

p.L251V

c.751C>G

1 paper

NM_024852.4

p.S254T

c.760T>A

1 paper

NM_024852.4

p.R256W

c.766C>T