Varaico: Literature-Extracted Genetic Variants

AGO3

77 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role ...

Pfam Domains

ArgoNaa 28–167UCSCN-terminal domain of argonaute

ArgoL1aa 177–227UCSCArgonaute linker 1 domain

PAZaa 234–366UCSCPAZ domain

ArgoL2aa 375–421UCSCArgonaute linker 2 domain

ArgoMidaa 430–512UCSCMid domain of argonaute

Piwiaa 518–819UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC catalytic component 3

HGNC Previous Symbol

EIF2C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024852.4

p.G302S

c.904G>A

Surrounding Variants

1 paper

NM_024852.4

p.L319V

c.955C>G

1 paper

NM_024852.4

p.Q320K

c.958C>A

1 paper

NM_024852.4

p.P324S

c.970C>T

2 papers

NM_024852.4

p.P324L

c.971C>T

1 paper

NM_024852.4

p.L326insFs

c.976_977insAT

2 papers

NM_024852.4

p.P327L

c.980C>T

1 paper

NM_024852.4

p.C328delFs

c.983_984delGT

2 papers

NM_024852.4

p.G332R

c.994G>A

2 papers

NM_024852.4

p.G332R

c.994G>C

1 paper

NM_024852.4

p.T338P

c.1012A>C

1 paper

NM_024852.4

p.T294Splc

c.881+1G>A

1 paper

NM_024852.4

p.A290S

c.868G>T