Varaico: Literature-Extracted Genetic Variants

AGO3

77 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role ...

Pfam Domains

ArgoNaa 28–167UCSCN-terminal domain of argonaute

ArgoL1aa 177–227UCSCArgonaute linker 1 domain

PAZaa 234–366UCSCPAZ domain

ArgoL2aa 375–421UCSCArgonaute linker 2 domain

ArgoMidaa 430–512UCSCMid domain of argonaute

Piwiaa 518–819UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC catalytic component 3

HGNC Previous Symbol

EIF2C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024852.4

p.R648Q

c.1943G>A

Surrounding Variants

1 paper

NM_024852.4

p.R648W

c.1942C>T

1 paper

NM_024852.4

p.Q653P

c.1958A>C

1 paper

NM_024852.4

p.A644delFs

c.1930delG

1 paper

NM_024852.4

p.K656Q

c.1966A>C

1 paper

NM_024852.4

p.E638A

c.1913A>C

1 paper

NM_024852.4

p.Q633H

c.1899G>C

1 paper

NM_024852.4

p.Q633H

c.1899G>T

1 paper

NM_024852.4

p.R664C

c.1990C>T

1 paper

NM_024852.4

p.R664H

c.1991G>A

1 paper

NM_024852.4

p.I665I

c.1995C>T

1 paper

NM_024852.4

p.V630I

c.1888G>A

1 paper

NM_024852.4

p.R669W

c.2005C>T