Varaico: Literature-Extracted Genetic Variants

AGO3

77 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role ...

Pfam Domains

ArgoNaa 28–167UCSCN-terminal domain of argonaute

ArgoL1aa 177–227UCSCArgonaute linker 1 domain

PAZaa 234–366UCSCPAZ domain

ArgoL2aa 375–421UCSCArgonaute linker 2 domain

ArgoMidaa 430–512UCSCMid domain of argonaute

Piwiaa 518–819UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC catalytic component 3

HGNC Previous Symbol

EIF2C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024852.4

p.R721S

c.2163G>C

Surrounding Variants

1 paper

NM_024852.4

p.R721S

c.2163G>T

1 paper

NM_024852.4

p.E723K

c.2167G>A

1 paper

NM_024852.4

p.C718F

c.2153G>T

1 paper

NM_024852.4

p.R715R

c.2145A>C

1 paper

NM_024852.4

p.Y699C

c.2096A>G

1 paper

NM_024852.4

p.C692C

c.2076C>T

1 paper

NM_024852.4

p.R689Q

c.2066G>A

3 papers

NM_024852.4

p.R689*

c.2065C>T

1 paper

NM_024852.4

p.Q679_V680Splc

c.2038-2A>T

1 paper

NM_024852.4

p.S673L

c.2018C>T

1 paper

NM_024852.4

p.R669Q

c.2006G>A

1 paper

NM_024852.4

p.R669W

c.2005C>T