Varaico: Literature-Extracted Genetic Variants

AGO4

79 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which contain PAZ and PIWI domains and play an integral role in RNA interference and short-interfering-RNA-mediated gene silencing. This ...

Pfam Domains

ArgoNaa 26–156UCSCN-terminal domain of argonaute

ArgoL1aa 166–216UCSCArgonaute linker 1 domain

PAZaa 221–355UCSCPAZ domain

ArgoL2aa 364–412UCSCArgonaute linker 2 domain

ArgoMidaa 421–503UCSCMid domain of argonaute

Piwiaa 509–820UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC component 4

HGNC Previous Symbol

EIF2C4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017629.4

p.M354I

c.1062G>C

Surrounding Variants

1 paper

NM_017629.4

p.M354I

c.1062G>A

1 paper

NM_017629.4

p.M354I

c.1062G>T

1 paper

NM_017629.4

p.A357V

c.1070C>T

1 paper

NM_017629.4

p.D364N

c.1090G>A

1 paper

NM_017629.4

p.I343I

c.1029C>T

1 paper

NM_017629.4

p.C342S

c.1025G>C

1 paper

NM_017629.4

p.C342S

c.1024T>A

1 paper

NM_017629.4

p.Q340del1

c.1018_1019delCAG

1 paper

NM_017629.4

p.G339E

c.1016G>A

1 paper

NM_017629.4

p.V333G

c.998T>G

1 paper

NM_017629.4

p.S375R

c.1123A>C

1 paper

NM_017629.4

p.S375R

c.1125C>A