Varaico: Literature-Extracted Genetic Variants

AGO4

79 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which contain PAZ and PIWI domains and play an integral role in RNA interference and short-interfering-RNA-mediated gene silencing. This ...

Pfam Domains

ArgoNaa 26–156UCSCN-terminal domain of argonaute

ArgoL1aa 166–216UCSCArgonaute linker 1 domain

PAZaa 221–355UCSCPAZ domain

ArgoL2aa 364–412UCSCArgonaute linker 2 domain

ArgoMidaa 421–503UCSCMid domain of argonaute

Piwiaa 509–820UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC component 4

HGNC Previous Symbol

EIF2C4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017629.4

p.Q628P

c.1883A>C

Surrounding Variants

1 paper

NM_017629.4

p.R627L

c.1880G>T

1 paper

NM_017629.4

p.R627G

c.1879C>G

1 paper

NM_017629.4

p.R627W

c.1879C>T

1 paper

NM_017629.4

p.Q632L

c.1895A>T

1 paper

NM_017629.4

p.Q638*

c.1912C>T

1 paper

NM_017629.4

p.E639K

c.1915G>A

1 paper

NM_017629.4

p.E639*

c.1915G>T

1 paper

NM_017629.4

p.R616Q

c.1847G>A

1 paper

NM_017629.4

p.R616W

c.1846C>T

1 paper

NM_017629.4

p.S615G

c.1843A>G

2 papers

NM_017629.4

p.H613P

c.1838A>C

1 paper

NM_017629.4

p.T645I

c.1934C>T