Varaico: Literature-Extracted Genetic Variants

AGO4

79 papers

RefSeq Summary

This gene encodes a member of the Argonaute family of proteins which contain PAZ and PIWI domains and play an integral role in RNA interference and short-interfering-RNA-mediated gene silencing. This ...

Pfam Domains

ArgoNaa 26–156UCSCN-terminal domain of argonaute

ArgoL1aa 166–216UCSCArgonaute linker 1 domain

PAZaa 221–355UCSCPAZ domain

ArgoL2aa 364–412UCSCArgonaute linker 2 domain

ArgoMidaa 421–503UCSCMid domain of argonaute

Piwiaa 509–820UCSCPiwi domain

Gene Aliases

HGNC Name

argonaute RISC component 4

HGNC Previous Symbol

EIF2C4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017629.4

p.Y807C

c.2420A>G

Surrounding Variants

1 paper

NM_017629.4

p.Y807F

c.2420A>T

1 paper

NM_017629.4

p.A808S

c.2422G>T

1 paper

NM_017629.4

p.Y806C

c.2417A>G

1 paper

NM_017629.4

p.R814K

c.2441G>A

1 paper

NM_017629.4

p.A815T

c.2443G>A

1 paper

NM_017629.4

p.S798S

c.2394A>C

1 paper

NM_017629.4

p.H818_D823del6

c.2452_2468del18

1 paper

NM_017629.4

p.H818N

c.2452C>A

1 paper

NM_017629.4

p.L784L

c.2352G>C

1 paper

NM_017629.4

p.L784P

c.2351T>C

1 paper

NM_017629.4

p.D779E

c.2337T>A

1 paper

NM_017629.4

p.D779E

c.2337T>G