Varaico: Literature-Extracted Genetic Variants

Gene:AGTR1
Variant:p.F66F

AGTR1

439 papers

RefSeq Summary

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts...

Pfam Domains

7tm_1aa 45–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

angiotensin II receptor type 1

HGNC Previous Symbol

AGTR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000685.5
p.F66F
c.198T>C
Surrounding Variants
1 paper
NM_000685.5
p.F66Y
c.197T>A
1 paper
NM_000685.5
p.L67R
c.200T>G
1 paper
NM_000685.5
p.L68M
c.202T>A
1 paper
NM_000685.5
p.V65L
c.193G>C
1 paper
NM_000685.5
p.S64N
c.191G>A
1 paper
NM_000685.5
p.L70*
c.209T>G
1 paper
NM_000685.5
p.V62V
c.186G>A
1 paper
NM_000685.5
p.L72M
c.214C>A
5 papers
NM_000685.5
p.A73T
c.217G>A
3 papers
NM_000685.5
p.D74N
c.220G>A
1 paper
NM_000685.5
p.D74Y
c.220G>T
2 papers
NM_000685.5
p.D74A
c.221A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."