Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.Y474*

c.1422C>A

Surrounding Variants

1 paper

NM_001382430.1

p.Y474*

c.1422C>G

1 paper

NM_001382430.1

p.S475T

c.1423T>A

1 paper

NM_001382430.1

p.Y474F

c.1421A>T

1 paper

NM_001382430.1

p.Y474S

c.1421A>C

1 paper

NM_001382430.1

p.Y474N

c.1420T>A

2 papers

NM_001382430.1

p.S475L

c.1424C>T

1 paper

NM_001382430.1

p.S475*

c.1424C>A

1 paper

NM_001382430.1

p.A476T

c.1426G>A

30 papers

NM_001382430.1

p.S473A

c.1417T>G

3 papers

NM_001382430.1

p.S473P

c.1417T>C

2 papers

NM_001382430.1

p.A476V

c.1427C>T

1 paper

NM_001382430.1

p.A476D

c.1427C>A