Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.P467A

c.1399C>G

Surrounding Variants

1 paper

NM_001382430.1

p.P467S

c.1399C>T

4 papers

NM_001382430.1

p.P467L

c.1400C>T

3 papers

NM_001382430.1

p.R466M

c.1397G>T

2 papers

NM_001382430.1

p.R466T

c.1397G>C

2 papers

NM_001382430.1

p.R466K

c.1397G>A

1 paper

NM_001382430.1

p.R466delins

c.1396_1397delinsTT

1 paper

NM_001382430.1

p.H468N

c.1402C>A

1 paper

NM_001382430.1

p.R466W

c.1396A>T

1 paper

NM_001382430.1

p.R465L

c.1394G>T

8 papers

NM_001382430.1

p.R465H

c.1394G>A

8 papers

NM_001382430.1

p.R465C

c.1393C>T

2 papers

NM_001382430.1

p.R465G

c.1393C>G