Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.D456Y

c.1366G>T

Surrounding Variants

1 paper

NM_001382430.1

p.D456N

c.1366G>A

2 papers

NM_001382430.1

p.D455G

c.1364A>G

1 paper

NM_001382430.1

p.D455A

c.1364A>C

1 paper

NM_001382430.1

p.S457I

c.1370G>T

1 paper

NM_001382430.1

p.S457T

c.1370G>C

1 paper

NM_001382430.1

p.M458L

c.1372A>T

1 paper

NM_001382430.1

p.M458V

c.1372A>G

1 paper

NM_001382430.1

p.M458L

c.1372A>C

9 papers

NM_001382430.1

p.M458T

c.1373T>C

1 paper

NM_001382430.1

p.M458K

c.1373T>A

1 paper

NM_001382430.1

p.M458I

c.1374G>T

1 paper

NM_001382430.1

p.M458_E459insFs

c.1374_1375ins13