Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E314_Y315del2

c.940_944del6

Surrounding Variants

1 paper

NM_001382430.1

p.Y315_L316insFs

c.945_946insC

1 paper

NM_001382430.1

p.L316fs

c.946_947fs

2 papers

NM_001382430.1

p.Y315F

c.944A>T

1 paper

NM_001382430.1

p.A317S

c.949G>T

1 paper

NM_001382430.1

p.A317insFs

c.949_950insA

1 paper

NM_001382430.1

p.A317P

c.949G>C

1 paper

NM_001382430.1

p.A317V

c.950C>T

1 paper

NM_001382430.1

p.A317delFs

c.949delC

2 papers

NM_001382430.1

p.A317A

c.951C>A

1 paper

NM_001382430.1

p.E314*

c.940G>T

1 paper

NM_001382430.1

p.P318A

c.952C>G

1 paper

NM_001382430.1

p.P318insFs

c.952_953insA