Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E314*

c.940G>T

Surrounding Variants

1 paper

NM_001382430.1

p.P313H

c.938C>A

1 paper

NM_001382430.1

p.P313S

c.937C>T

2 papers

NM_001382430.1

p.P313A

c.937C>G

1 paper

NM_001382430.1

p.G311_T312del2

c.931_935del6

1 paper

NM_001382430.1

p.F309_T312del4

c.925_935del12

2 papers

NM_001382430.1

p.Y315F

c.944A>T

4 papers

NM_001382430.1

p.T312I

c.935C>T

1 paper

NM_001382430.1

p.E314_Y315del2

c.940_944del6

3 papers

NM_001382430.1

p.T312A

c.934A>G

1 paper

NM_001382430.1

p.Y315_L316insFs

c.945_946insC

1 paper

NM_001382430.1

p.G311G

c.933C>T

1 paper

NM_001382430.1

p.L316fs

c.946_947fs