Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001382430.1

p.M306T

c.917T>C

Surrounding Variants

2 papers

NM_001382430.1

p.M306I

c.918G>T

2 papers

NM_001382430.1

p.M306I

c.918G>C

2 papers

NM_001382430.1

p.M306I

c.918G>A

1 paper

NM_001382430.1

p.M306L

c.916A>T

1 paper

NM_001382430.1

p.M306V

c.916A>G

1 paper

NM_001382430.1

p.M306L

c.916A>C

1 paper

NM_001382430.1

p.K307E

c.919A>G

1 paper

NM_001382430.1

p.T305S

c.914C>G

2 papers

NM_001382430.1

p.K307N

c.921G>T

2 papers

NM_001382430.1

p.K307N

c.921G>C

1 paper

NM_001382430.1

p.K307K

c.921G>A

3 papers

NM_001382430.1

p.T305A

c.913A>G