Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E298*

c.892G>T

Surrounding Variants

1 paper

NM_001382430.1

p.E298A

c.893A>C

2 papers

NM_001382430.1

p.E298D

c.894G>T

1 paper

NM_001382430.1

p.E298D

c.894G>C

1 paper

NM_001382430.1

p.K297R

c.890A>G

1 paper

NM_001382430.1

p.G299W

c.895G>T

1 paper

NM_001382430.1

p.G299R

c.895G>A

1 paper

NM_001382430.1

p.C296F

c.887G>T

1 paper

NM_001382430.1

p.G299delFs

c.895_896delCC

2 papers

NM_001382430.1

p.I300N

c.899T>A

1 paper

NM_001382430.1

p.L295L

c.885G>T

1 paper

NM_001382430.1

p.L295L

c.885G>C

1 paper

NM_001382430.1

p.L295V

c.883C>G