Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001382430.1

p.T291A

c.871A>G

Surrounding Variants

1 paper

NM_001382430.1

p.T291S

c.871A>T

1 paper

NM_001382430.1

p.I290fs

c.868_869fs

1 paper

NM_001382430.1

p.I290I

c.870C>A

1 paper

NM_001382430.1

p.I290delFs

c.868delT

1 paper

NM_001382430.1

p.I290V

c.868A>G

1 paper

NM_001382430.1

p.K289delFs

c.867delC

1 paper

NM_001382430.1

p.D292G

c.875A>G

1 paper

NM_001382430.1

p.D292A

c.875A>C

1 paper

NM_001382430.1

p.D292D

c.876C>T

1 paper

NM_001382430.1

p.K289insFs

c.866_867insCT

1 paper

NM_001382430.1

p.F293I

c.877T>A

1 paper

NM_001382430.1

p.K289fs

c.865_866fs