Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.L280fs

c.838_839fs

Surrounding Variants

1 paper

NM_001382430.1

p.L280L

c.840C>A

1 paper

NM_001382430.1

p.L280delFs

c.839_840delGA

1 paper

NM_001382430.1

p.L280F

c.838C>T

4 papers

NM_001382430.1

p.L282L

c.844C>T

1 paper

NM_001382430.1

p.L282V

c.844C>G

1 paper

NM_001382430.1

p.N279S

c.836A>G

1 paper

NM_001382430.1

p.N279D

c.835A>G

2 papers

NM_001382430.1

p.E278A

c.833A>C

2 papers

NM_001382430.1

p.E278Q

c.832G>C

1 paper

NM_001382430.1

p.L282_D283Fs

c.846_848delinsTGFs

1 paper

NM_001382430.1

p.L277delFs

c.830delA

1 paper

NM_001382430.1

p.D283delFs

c.848delT