Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001382430.1

p.K189N

c.567G>T

Surrounding Variants

3 papers

NM_001382430.1

p.K189N

c.567G>C

1 paper

NM_001382430.1

p.K189delFs

c.565delT

1 paper

NM_001382430.1

p.K189M

c.566A>T

3 papers

NM_001382430.1

p.K189T

c.566A>C

4 papers

NM_001382430.1

p.K189_D190Splc

c.567+2T>G

1 paper

NM_001382430.1

p.A188G

c.563C>G

1 paper

NM_001382430.1

p.A188P

c.562G>C

5 papers

NM_001382430.1

p.A188T

c.562G>A

1 paper

NM_001382430.1

p.K189_D190Splc

c.567+5G>A

1 paper

NM_001382430.1

p.V187V

c.561G>C

1 paper

NM_001382430.1

p.V187L

c.559G>C

4 papers

NM_001382430.1

p.V187M

c.559G>A