Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.K183E

c.547A>G

Surrounding Variants

1 paper

NM_001382430.1

p.K183*

c.547A>T

1 paper

NM_001382430.1

p.K182insFs

c.545_546insA

2 papers

NM_001382430.1

p.K183R

c.548A>G

1 paper

NM_001382430.1

p.K183N

c.549G>T

1 paper

NM_001382430.1

p.K183N

c.549G>C

2 papers

NM_001382430.1

p.K182R

c.545A>G

1 paper

NM_001382430.1

p.E184K

c.550G>A

1 paper

NM_001382430.1

p.E184E

c.552A>G

1 paper

NM_001382430.1

p.V185F

c.553G>T

2 papers

NM_001382430.1

p.V185I

c.553G>A

1 paper

NM_001382430.1

p.K170_E184del15

c.508_551del45

1 paper

NM_001382430.1

p.L181F

c.541C>T