Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.G159G

c.477C>A

Surrounding Variants

2 papers

NM_001382430.1

p.G159V

c.476G>T

1 paper

NM_001382430.1

p.G159D

c.476G>A

3 papers

NM_001382430.1

p.T160A

c.478A>G

1 paper

NM_001382430.1

p.G159R

c.475G>C

1 paper

NM_001382430.1

p.G159S

c.475G>A

1 paper

NM_001382430.1

p.T160T

c.480T>G

1 paper

NM_001382430.1

p.F161L

c.481T>C

1 paper

NM_001382430.1

p.K158R

c.473A>G

1 paper

NM_001382430.1

p.F161S

c.482T>C

1 paper

NM_001382430.1

p.K158*

c.472A>T

1 paper

NM_001382430.1

p.F161L

c.483C>G

1 paper

NM_001382430.1

p.F161L

c.483C>A