Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E149E

c.447G>A

Surrounding Variants

1 paper

NM_001382430.1

p.E149A

c.446A>C

1 paper

NM_001382430.1

p.E149*

c.445G>T

1 paper

NM_001382430.1

p.E149K

c.445G>A

1 paper

NM_001382430.1

p.N148delFs

c.444delG

3 papers

NM_001382430.1

p.F150L

c.450T>A

1 paper

NM_001382430.1

p.E151Q

c.451G>C

3 papers

NM_001382430.1

p.E151K

c.451G>A

1 paper

NM_001382430.1

p.N148fs

c.442_443fs

2 papers

NM_001382430.1

p.M147T

c.440T>C

1 paper

NM_001382430.1

p.T146T

c.438C>G

1 paper

NM_001382430.1

p.T146_M147insFs

c.438_439ins10

3 papers

NM_001382430.1

p.T146I

c.437C>T