Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.P141P

c.423C>G

Surrounding Variants

1 paper

NM_001382430.1

p.P141P

c.423C>A

1 paper

NM_001382430.1

p.P141S

c.421C>T

1 paper

NM_001382430.1

p.P141T

c.421C>A

1 paper

NM_001382430.1

p.K142M

c.425A>T

1 paper

NM_001382430.1

p.K140N

c.420G>C

1 paper

NM_001382430.1

p.K140delFs

c.419delT

3 papers

NM_001382430.1

p.H143Y

c.427C>T

1 paper

NM_001382430.1

p.H143P

c.428A>C

1 paper

NM_001382430.1

p.H143H

c.429C>T

2 papers

NM_001382430.1

p.K142_H143delFs

c.424_427del4

4 papers

NM_001382430.1

p.R144C

c.430C>T

2 papers

NM_001382430.1

p.A139V

c.416C>T