Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.S137F

c.410C>T

Surrounding Variants

1 paper

NM_001382430.1

p.S137Y

c.410C>A

1 paper

NM_001382430.1

p.S137A

c.409T>G

1 paper

NM_001382430.1

p.S137T

c.409T>A

1 paper

NM_001382430.1

p.L138M

c.412C>A

1 paper

NM_001382430.1

p.V136A

c.407T>C

9 papers

NM_001382430.1

p.V136M

c.406G>A

1 paper

NM_001382430.1

p.L138L

c.414G>A

1 paper

NM_001382430.1

p.E133_M134del2

c.397_401del6

3 papers

NM_001382430.1

p.E135D

c.405G>C

2 papers

NM_001382430.1

p.A139P

c.415G>C

1 paper

NM_001382430.1

p.A139T

c.415G>A

2 papers

NM_001382430.1

p.A139V

c.416C>T