Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.M134K

c.401T>A

Surrounding Variants

1 paper

NM_001382430.1

p.M134T

c.401T>C

2 papers

NM_001382430.1

p.M134I

c.402G>T

2 papers

NM_001382430.1

p.M134I

c.402G>C

2 papers

NM_001382430.1

p.M134I

c.402G>A

1 paper

NM_001382430.1

p.M134L

c.400A>T

1 paper

NM_001382430.1

p.M134L

c.400A>C

5 papers

NM_001382430.1

p.E133D

c.399G>T

4 papers

NM_001382430.1

p.E133D

c.399G>C

1 paper

NM_001382430.1

p.E135V

c.404A>T

3 papers

NM_001382430.1

p.E135G

c.404A>G

3 papers

NM_001382430.1

p.E135D

c.405G>C

1 paper

NM_001382430.1

p.E133K

c.397G>A