Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001382430.1

p.G130V

c.389G>T

Surrounding Variants

3 papers

NM_001382430.1

p.G130A

c.389G>C

3 papers

NM_001382430.1

p.G130E

c.389G>A

1 paper

NM_001382430.1

p.S129_G130delFs

c.387_388delCT

1 paper

NM_001382430.1

p.G130W

c.388G>T

1 paper

NM_001382430.1

p.G130R

c.388G>A

1 paper

NM_001382430.1

p.A131S

c.391G>T

1 paper

NM_001382430.1

p.A131P

c.391G>C

4 papers

NM_001382430.1

p.A131T

c.391G>A

1 paper

NM_001382430.1

p.S129L

c.386C>T

1 paper

NM_001382430.1

p.A131D

c.392C>A

1 paper

NM_001382430.1

p.G130delFs

c.389delC

1 paper

NM_001382430.1

p.S129_A131delFs

c.385_391del7