Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.N128K

c.384C>G

Surrounding Variants

1 paper

NM_001382430.1

p.N128K

c.384C>A

1 paper

NM_001382430.1

p.S129A

c.385T>G

1 paper

NM_001382430.1

p.S129P

c.385T>C

1 paper

NM_001382430.1

p.S129T

c.385T>A

1 paper

NM_001382430.1

p.N128S

c.383A>G

1 paper

NM_001382430.1

p.S129L

c.386C>T

1 paper

NM_001382430.1

p.G130W

c.388G>T

1 paper

NM_001382430.1

p.G130R

c.388G>A

2 papers

NM_001382430.1

p.G130V

c.389G>T

3 papers

NM_001382430.1

p.G130A

c.389G>C

3 papers

NM_001382430.1

p.G130E

c.389G>A

1 paper

NM_001382430.1

p.D127N

c.379G>A