Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001382430.1

p.R121W

c.361C>T

Surrounding Variants

1 paper

NM_001382430.1

p.R121Q

c.362G>A

1 paper

NM_001382430.1

p.R121R

c.363G>A

1 paper

NM_001382430.1

p.S122A

c.364T>G

3 papers

NM_001382430.1

p.S122L

c.365C>T

1 paper

NM_001382430.1

p.D119E

c.357C>G

2 papers

NM_001382430.1

p.D119G

c.356A>G

1 paper

NM_001382430.1

p.R121_S122del2

c.361_365del6

2 papers

NM_001382430.1

p.G123D

c.368G>A

1 paper

NM_001382430.1

p.E115_E117delFs

c.344_351del8

1 paper

NM_001382430.1

p.S124A

c.370T>G

1 paper

NM_001382430.1

p.S124P

c.370T>C

1 paper

NM_001382430.1

p.E117_M118delins

c.351_352delinsCT