Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E115_E117delFs

c.344_351del8

Surrounding Variants

1 paper

NM_001382430.1

p.E117_M118delins

c.351_352delinsCT

11 papers

NM_001382430.1

p.E117del1

c.349_351delCTC

2 papers

NM_001382430.1

p.E117D

c.351G>T

1 paper

NM_001382430.1

p.E117D

c.351G>C

2 papers

NM_001382430.1

p.D119G

c.356A>G

1 paper

NM_001382430.1

p.E117G

c.350A>G

1 paper

NM_001382430.1

p.E117*

c.349G>T

1 paper

NM_001382430.1

p.E117K

c.349G>A

1 paper

NM_001382430.1

p.D119E

c.357C>G

1 paper

NM_001382430.1

p.E116*

c.346G>T

4 papers

NM_001382430.1

p.E116K

c.346G>A

1 paper

NM_001382430.1

p.E115E

c.345G>A