Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E115insFs

c.344_345insC

Surrounding Variants

1 paper

NM_001382430.1

p.E115E

c.345G>A

1 paper

NM_001382430.1

p.E115K

c.343G>A

1 paper

NM_001382430.1

p.L110_E114del5

c.328_341del15

1 paper

NM_001382430.1

p.E116*

c.346G>T

4 papers

NM_001382430.1

p.E116K

c.346G>A

1 paper

NM_001382430.1

p.Q113insFs

c.339dupG

1 paper

NM_001382430.1

p.E114*

c.340G>T

6 papers

NM_001382430.1

p.E114Q

c.340G>C

1 paper

NM_001382430.1

p.E117*

c.349G>T

1 paper

NM_001382430.1

p.E117K

c.349G>A

1 paper

NM_001382430.1

p.E117G

c.350A>G

1 paper

NM_001382430.1

p.Q113R

c.338A>G