Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.K112*

c.334A>T

Surrounding Variants

3 papers

NM_001382430.1

p.K111N

c.333G>T

4 papers

NM_001382430.1

p.K111N

c.333G>C

1 paper

NM_001382430.1

p.K112N

c.336G>T

1 paper

NM_001382430.1

p.Q113E

c.337C>G

2 papers

NM_001382430.1

p.K111del1

c.331_332delCTT

6 papers

NM_001382430.1

p.K111E

c.331A>G

1 paper

NM_001382430.1

p.L110del1

c.328_330delGAG

1 paper

NM_001382430.1

p.L110L

c.330C>T

1 paper

NM_001382430.1

p.Q113R

c.338A>G

1 paper

NM_001382430.1

p.E114*

c.340G>T

6 papers

NM_001382430.1

p.E114Q

c.340G>C

1 paper

NM_001382430.1

p.L110F

c.328C>T